Jacques Simard

Professor, Deputy Director of Basic Research
CHU de Quebec Research Center

Jacques Simard holds a Canada Research Chair in Oncogenetics, is a Professor, Department of Molecular Medicine at the Université Laval, Deputy Director of Basic Research at the CHU de Quebec Research Center. He was author on more than 330 publications. His career as an independent investigator began in 1990. A major emphasis of his research program has been the biosynthesis and action of steroid hormones in target tissues, as well as the characterization of the molecular basis of a form of congenital adrenal hyperplasia and male pseudohermaphroditism. In acknowledgment of his outstanding contributions, in 1999 the most prestigious recognition for a scientist younger than 40, was awarded by the Endocrine Society. He also received le Prix du jeune Chercheur André Dupont du Club de Recherches Cliniques du Québec in 1997 and the Prix d’Excellence 2004 de la Fondation des maladies infantiles. In parallel, he was also involved in the characterization of the impact of mutations in susceptibility genes for breast and ovarian cancers, namely BRCA1 and BRCA2. Since 2001, he has been Director of the Interdisciplinary Health Research International Team on Breast Cancer susceptibility (INHERIT BRCAs), which has been renewed in 2008 as the CIHR Team in Familial Risks of Breast Cancer, a CIHR clinical research network including 26 scientists and clinicians from Quebec, Ontario, Alberta and British Columbia, New Brunswick, USA, UK and France. This team received the Mérites du CQLC 2003 awarded by the Conseil Québecois de lutte contre le cancer, an agency of the Ministère de la santé et des services sociaux du Québec.

During the last few years, his team has extended their international networks to boost the capacity to perform robust genetic epidemiological assessment of the role of individual genetic variants in disease risk and how such a risk may be modified by interactions with other genes, environmental and lifestyle factors. He also played a key role in strategic development of health research as member of the Medical Research Council of Canada, the Ministerial Science Advisory Board of Health Canada, the Canadian Breast Cancer Research Alliance Management Committee and the Institute Advisory Board of the CIHR Gender and Health Institute, and Genome Canada Board of Directors. He is currently Chair of the Science and Industry Advisory Committee of Genome Canada and a member of the Conseil sectoriel Nouvelle Économie du Fonds de Solidarité FTQ, a key labour-sponsored investment fund in life sciences in Canada. He is also Fellow of the Canadian Academy of Health Sciences.

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